Anakinra in systemic juvenile idiopathic arthritis (soJIA) non responsive to antiTNF
نویسندگان
چکیده
Methods Sixteen patients affected by SoJIA (12 F, 4 M) were switched to Anakinra. Patients received Anakinra (in association with MTX) at the dose of 100 mg daily (> 50 kg) or at the dose of 1–2 mg/kg daily (< 50 kg). All patients failed previous DMARDS and TNF inhibitors. Paediatric patients were evaluated according to the ACR30 paediatric criteria. Adults were evaluated according to EULAR criteria (DAS). We also considered clinical parameters as fever, rash, adenopathy and organomegaly.
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